Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immune-Related Genomic Schizophrenic Subtyping Identified in DLPFC Transcriptome

4 Jul 2022

Abstract excerpt

Well-documented evidence of the physiologic, genetic, and behavioral heterogeneity of schizophrenia suggests that diagnostic subtyping may clarify the underlying pathobiology of the disorder. Recent studies have demonstrated that increased inflammation may be a prominent feature of a subset of schizophrenics. However, these findings are inconsistent, possibly due to evaluating schizophrenics as a single group. In...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bipolar Disorder and Treatment
Share to Neuroinflammation and Neurodegeneration Mechanisms
Share to Tryptophan and brain disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35885983
DOI: 10.3390/genes13071200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immune-Related Genomic Schizophrenic Subtyping Identified in DLPFC TranscriptomePMID 35885983Read ↗

DLPFC transcriptome defines two molecular subtypes of schizophreniaSemantic proximity Read ↗

DLPFC Transcriptome Defines Two Molecular Subtypes of SchizophreniaSemantic proximity Read ↗

Inflammation-related genes up-regulated in schizophrenia brainsSemantic proximity Read ↗

Neuroimmune transcriptome changes in brains of psychiatric and neurological disorder patientsSemantic proximity Read ↗

Markers of inflammation and stress distinguish subsets of individuals with schizophrenia and bipolar disorderSemantic proximity Read ↗

Innate immune response is differentially dysregulated between bipolar disease and schizophreniaSemantic proximity Read ↗

Patients with schizophrenia and bipolar disorder display a similar global gene expression signature in whole blood that reflects elevated proportion of immature neutrophil cells with association to lipid changesSemantic proximity Read ↗

Inflammatory gene expression in monocytes of patients with schizophrenia: overlap and difference with bipolar disorder. A study in naturalistically treated patientsSemantic proximity Read ↗

A subtype of schizophrenia patients with altered methylation level of genes related to immune cell activitySemantic proximity Read ↗

The impact of sex on gene expression in the brain of schizophrenic patients: a systematic review and meta-analysis of transcriptomic studiesSemantic proximity Read ↗

Mapping spatially organized molecular and genetic signatures of schizophrenia across multiple scales in human prefrontal cortexSemantic proximity Read ↗

The impact of sex on gene expression in the brain of schizophrenic patients: a systematic review and meta-analysis of transcriptomic studiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.