Article

Engineering a hybrid 3D construct for bone regeneration to promote simultaneous pre-vascularization and osteogenic differentiation in vitro

2026-05-09

Abstract excerpt

Critical-sized bone defects represent a challenge in bone tissue engineering, due to insufficient vascularization that results in implant failure. Scaffold pre-vascularization is a promising strategy to create a functional microvascular network that integrates with host vasculature. In this study, we present a hybrid 3D construct comprising a hyaluronic acid-based hydrogel and a 3D printed polycaprolactone/β-trica...

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Literature Corpus work: 26019ce0-e75a-57f9-8b93-8a46b09d540d
DOI: 10.64898/2026.05.06.723258

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