Article

Macular single-nucleus transcriptomics shows preservation of ganglion cells in dry AMD

2026-04-24

Abstract excerpt

<title>Abstract</title> <p>Age-related macular degeneration (AMD) is classically defined by photoreceptor and retinal pigment epithelium degeneration; however, increasing evidence suggests that retinal ganglion cells (RGCs) may also be affected. The RGCs, including intrinsically photosensitive RGCs (ipRGCs), play essential roles in visual and non-image-forming functions, yet their vulnerability in the human dry A...

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Literature Corpus work: d860006c-2c7f-5119-83b7-964b7a2881ec
DOI: 10.21203/rs.3.rs-9074583/v1

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