Article

Comprehensive Analysis of Aneuploidy Status and Its Effect on Efficacy of EGFR-TKIs in Lung Cancer

2021-09-07

Abstract excerpt

<h4>Background: </h4> The evaluation of the clinical efficacy of molecularly targeted cancer therapies remains a great challenge. <h4>Methods: </h4>: Next-generation sequencing (NGS) analysis and fluorescence in situ hybridization (FISH) were used to evaluate the clinical efficacy in terms of EGFR mutation abundance and aneuploidy status. <h4>Results: </h4> The PFS of patients diagnosed as euploidy was actually hi...

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Literature Corpus work: d84d624c-3294-5824-a2a6-db49a3bfdd2d
DOI: 10.21203/rs.3.rs-845098/v1

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