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Rgg2/Rgg3 quorum sensing is a determinant of <i>Streptococcus pyogenes</i> -host interactions in a murine intact skin infection model

2023-07-17

Abstract excerpt

Streptococcus pyogenes is an obligate human pathobiont associated with many disease states. Here, we present a novel model of S. pyogenes infection using intact murine epithelium. From this model, we were able to perform RNA sequencing to evaluate the genetic changes undertaken by both the bacterium and host at 5- and 24-hours post infection. Analysis of these genomic data demonstrate that S. pyogenes undergoes...

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Literature Corpus work
d83a3c47-2609-5743-881c-0eb290b00b12
DOI
10.1101/2023.07.14.549100
Open publication

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Rgg2/Rgg3 quorum sensing is a determinant of <i>Streptococcus pyogenes</i> -host interactions in a murine intact skin infection modelDOI 10.1101/2023.07.14.549100
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