Article

A <i>Streptococcus</i> quorum sensing system enables suppression of innate immunity

2020-12-04

Abstract excerpt

Some bacterial pathogens utilize cell-cell communication systems, such as quorum sensing (QS), to coordinate genetic programs during host colonization and infection. The human-restricted pathosymbiont Streptococcus pyogenes (Group A Streptococcus, GAS) uses the Rgg2/Rgg3 QS system to modify the bacterial surface, enabling biofilm formation and lysozyme resistance. Here, we demonstrate that innate immune cell resp...

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Literature Corpus work: df27af66-2fc2-53cf-904c-3f5ddba0b208
DOI: 10.1101/2020.12.03.411157

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