Article

Drug Repurposing of β-blocker Propranolol in Osteosarcoma: Preclinical Antitumor Efficacy Alone or in Combination with Chemotherapy.

2020-07-22

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Osteosarcoma is still associated with poor response to therapy and alarmingly elevated mortality rates, especially in developing countries, highlighting the urgent need of novel therapeutic strategies. Given that β-adrenergic receptor (β-AR) signaling regulates many cellular processes involved in the initiation and progression of cancer, multiple efforts have be...

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Literature Corpus work: d830b3ec-1cec-5be2-99f1-4622547f7514
DOI: 10.21203/rs.3.rs-44912/v1

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