Article

An efficient error correction and accurate assembly tool for noisy long reads

2023-03-12

Abstract excerpt

Long read sequencing data, particularly those derived from the Oxford Nanopore (ONT) sequencing platform, tend to exhibit a high error rate. Here, we present NextDenovo, a highly efficient error correction and assembly tool for noisy long reads, which achieves a high level of accuracy in genome assembly. NextDenovo can rapidly correct reads; these corrected reads contain fewer errors than other comparable tools an...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d80aa74d-47a8-5a6b-93e8-692cffb9df29
DOI: 10.1101/2023.03.09.531669

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

An efficient error correction and accurate assembly tool for noisy long readsDOI 10.1101/2023.03.09.531669Read

Fast and accurate assembly of Nanopore reads via progressive error correction and adaptive read selectionSemantic proximity Read

Highly-accurate long-read sequencing improves variant detection and assembly of a human genomeSemantic proximity Read

LongStitch: High-quality genome assembly correction and scaffolding using long readsSemantic proximity Read

Benchmarking long-read aligners and SV callers for structural variation detection in Oxford nanopore sequencing data.Semantic proximity Read

HiCanu: accurate assembly of segmental duplications, satellites, and allelic variants from high-fidelity long reads.Semantic proximity Read

Localized assembly for long reads enables genome-wide analysis of repetitive regions at single-base resolution in human genomesSemantic proximity Read

Benchmarking of bioinformatics tools for the hybrid de novo assembly of human whole-genome sequencing dataSemantic proximity Read

Localized assembly for long reads enables genome-wide analysis of repetitive regions at single-base resolution in human genomesSemantic proximity Read

Telomere-to-Telomere Phased Genome Assembly Using HERRO-Corrected Simplex Nanopore ReadsSemantic proximity Read

Investigating the performance of Oxford Nanopore long-read sequencing with respect to Illumina microarrays and short-read sequencingSemantic proximity Read

HiCanu: accurate assembly of segmental duplications, satellites, and allelic variants from high-fidelity long readsSemantic proximity Read

Sensitive alignment using paralogous sequence variants improves long read mapping and variant calling in segmental duplicationsSemantic proximity Read