Article

Genes identified in rodent studies of alcohol intake are enriched for heritability of human substance use

2021-03-23

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Rodent paradigms and human genome-wide association studies (GWASs) on drug use have the potential to provide biological insight into the pathophysiology of addiction. <h4>Methods</h4> Using GeneWeaver, we created rodent alcohol and nicotine gene-sets derived from 19 gene expression studies on alcohol and nicotine outcomes. We partitioned the SNP-heritability of these gene-s...

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Literature Corpus work: d7ac4353-95e1-5af4-97f9-3030416032d1
DOI: 10.1101/2021.03.22.436527

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