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An <i>ex vivo</i> human precision-cut lung slice platform provides insight into SARS-CoV-2 pathogenesis and antiviral drug efficacy

2023-04-19

Abstract excerpt

<h4>ABSTRACT</h4> COVID-19 has claimed millions of lives since the emergence of SARS-CoV-2, and lung disease appears the primary cause of the death in COVID-19 patients. However, the underlying mechanisms of COVID-19 pathogenesis remain elusive, and there is no existing model where the human disease can be faithfully recapitulated and conditions for the infection process can be experimentally controlled. Herein w...

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Literature Corpus work
d7693c6d-cfca-5f29-9fa2-2a7de11d050f
DOI
10.1101/2023.04.18.537373
Open publication

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An <i>ex vivo</i> human precision-cut lung slice platform provides insight into SARS-CoV-2 pathogenesis and antiviral drug efficacyDOI 10.1101/2023.04.18.537373
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