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Article

Cell-type-specific epigenetic effects of early life stress on the brain

10 Aug 2022

Abstract excerpt

Early life stress (ELS) induces long-term phenotypic adaptations that contribute to increased vulnerability to a host of neuropsychiatric disorders. Epigenetic mechanisms, including DNA methylation, histone modifications and non-coding RNA, are a proposed link between environmental stressors, alterations in gene expression, and phenotypes. Epigenetic modifications play a primary role in shaping functional...

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PMID: 35948532
DOI: 10.1038/s41398-022-02076-9

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