Article

NINJ1 plays a vital role in the release of neutrophil extracellular traps in acute lung injury

2026-01-13

Abstract excerpt

<title>Abstract</title> <p>Excessive neutrophil extracellular traps (NETs) formation is a significant contributor to acute lung injury (ALI), making its inhibition a novel therapeutic avenue to improve outcomes. In this study, we revealed that a novel pore-forming protein ninjurin-1 (NINJ1) was predominantly highly expressed in pro-inflammatory neutrophil subpopulations during ALI, using public single-cell RNA se...

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Literature Corpus work: d717fbe5-816b-5554-82f0-e8f4b17dd1a7
DOI: 10.21203/rs.3.rs-8426344/v1

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