Article

The assembly of neutrophil inflammasomes during COVID-19 is mediated by type I interferons

2023-09-08

Abstract excerpt

The severity of COVID-19 is linked to excessive inflammation. Neutrophils represent a critical arm of the innate immune response and are major mediators of inflammation, but their role in COVID-19 pathophysiology remains poorly understood. We conducted transcriptomic profiling of neutrophils obtained from patients with mild and severe COVID-19, as well as from SARS-CoV-2 infected mice, in comparison to non-infecte...

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Literature Corpus work: 9fdf63a7-04ea-5625-9669-a7b42046777e
DOI: 10.1101/2023.09.07.23295190

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