Article
RNA Profiling of Neuropathic Pain-Associated Human DRGs Reveal Sex-differences in Neuro-immune Interactions Promoting Pain
2021-11-27
Abstract excerpt
Neuropathic pain is a leading cause of high impact pain, is often disabling and is poorly managed by current therapeutics. Here we focused on a unique group of neuropathic pain patients undergoing thoracic vertebrectomy where the DRG is removed as part of the surgery allowing for molecular characterization and identification of mechanistic drivers of neuropathic pain independently of preclinical models. Our goal w...
Topics
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- Exercise and Physiological Responses
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Hormonal and reproductive studies
- Inflammatory mediators and NSAID effects
- Neuroinflammation and Neurodegeneration Mechanisms
- Neuropeptides and Animal Physiology
- Pain Mechanisms and Treatments
- Pharmacological Effects of Natural Compounds
Identifiers and source
- Literature Corpus work
- d6da9915-a255-5b06-ac91-a0b146ee32c1
- DOI
- 10.1101/2021.11.27.470190
