Article

Transcriptome analysis of the human tibial nerve identifies sexually dimorphic expression of genes involved in pain, inflammation and neuro-immunity

2018-10-23

Abstract excerpt

Sex differences in gene expression are important contributors to normal physiology and mechanisms of disease. This is increasingly apparent in understanding and potentially treating chronic pain where molecular mechanisms driving sex differences in neuronal plasticity are giving new insight into why certain chronic pain disorders preferentially affect women versus men. Large transcriptomic resources are increasing...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5d011ac6-8ba4-5155-a057-03ec27fbe5a1
DOI: 10.1101/450197

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Transcriptome analysis of the human tibial nerve identifies sexually dimorphic expression of genes involved in pain, inflammation and neuro-immunityDOI 10.1101/450197Read

Transcriptome Analysis of the Human Tibial Nerve Identifies Sexually Dimorphic Expression of Genes Involved in Pain, Inflammation, and Neuro-ImmunitySemantic proximity Read

RNA profiling of human dorsal root ganglia reveals sex differences in mechanisms promoting neuropathic painSemantic proximity Read

RNA Profiling of Neuropathic Pain-Associated Human DRGs Reveal Sex-differences in Neuro-immune Interactions Promoting PainSemantic proximity Read

Sex differences in gene regulation in the dorsal root ganglion after nerve injurySemantic proximity Read

Multi-omic integration with human dorsal root ganglia proteomics highlights TNFα signalling as a relevant sexually dimorphic pathwaySemantic proximity Read

Conserved transcriptional programming across sex and species after peripheral nerve injury predicts treatments for neuropathic painSemantic proximity Read

Sex-stratified genome-wide association study of multisite chronic pain in UK Biobank.Semantic proximity Read

Sex-Stratified Genome-Wide Association Study of Multisite Chronic Pain in UK BiobankSemantic proximity Read

Multi-omic integration with human DRG proteomics highlights TNFα signalling as a relevant sexually dimorphic pathwaySemantic proximity Read

Chronic pain gene expression changes in the brain and relationships with clinical traitsSemantic proximity Read

A transcriptional toolbox for exploring peripheral neuroimmune interactionsSemantic proximity Read

Investigation of cellular and molecular changes linked with neuropathic pain in healthy and injured human trigeminal nervesSemantic proximity Read