Article

Engineering cell fate with adaptive feedback control

2024-11-29

Abstract excerpt

Engineering cell fate is fundamental for optimizing stem cell-based therapies aimed at replacing cells in patients suffering from trauma or disease. By timely administering molecular regulators - such as transcription factors, RNAs, or small molecules - in a process that mimics in vivo embryonic development, stem cell differentiation can be guided toward a specific cell fate. A significant challenge in scaling up...

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Literature Corpus work: d6c1f83e-9ea0-5104-bfa4-a53dcb08de25
DOI: 10.1101/2024.11.29.625974

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