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MOV10 inhibits SADS-CoV replication by enhancing TRIM24-mediated K63-linked TRAF3 ubiquitination and this inhibition is antagonized by viral N protein

2026-01-10

Abstract excerpt

The global outbreak of SARS-CoV-2 has resulted in a renewed focus on coronaviruses with the potential for cross-species transmission and mutation risks. In particular, swine acute diarrhea syndrome coronavirus (SADS-CoV), potentially originating from intermediate horseshoe bat ( Rhinolophus affinis ), is a novel coronavirus that causes acute diarrhea, vomiting, and high mortality in suckling piglets. Innate immun...

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Literature Corpus work
d6c0fa89-ea5c-5231-8959-c7bf2c7a6457
DOI
10.64898/2026.01.09.698592
Open publication

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MOV10 inhibits SADS-CoV replication by enhancing TRIM24-mediated K63-linked TRAF3 ubiquitination and this inhibition is antagonized by viral N proteinDOI 10.64898/2026.01.09.698592
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