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African Swine Fever Virus pI215L Inhibits Type I Interferon Signaling by Targeting Interferon Regulatory Factor 9 for Autophagic Degradation

16 Aug 2022

Abstract excerpt

African swine fever virus (ASFV) causes a highly contagious and lethal disease in pigs and wild boars that is currently present in many countries, severely affecting the global pig industry. Despite extensive research, effective vaccines and antiviral strategies are still lacking, and many fundamental questions regarding the molecular mechanisms underlying host innate immunity escape remain unclear. In this...

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PMID: 35972295
DOI: 10.1128/jvi.00944-22

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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