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Homogeneously crosslinked <i>in situ</i> hydrogel enclosing high-density human-cancer cells promotes vascularized <i>in vivo</i> tumor modeling for immune cell therapy

2024-12-20

Abstract excerpt

<h4>ABSTRACT</h4> Cancer models in animal studies play a central role in cancer research, particularly in investigating vascularized tumor tissues for the validation of immune cell therapies. However, xenografts relying solely on cancer cells are ineffective for optimal tumor tissue formation. Additionally, tumor modeling using hydrogels with cancer cells to promote vascularization often leaves behind residual bi...

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Literature Corpus work
d695f01e-8283-50a5-bc9c-06e12384c234
DOI
10.1101/2024.12.17.628981
Open publication

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Homogeneously crosslinked <i>in situ</i> hydrogel enclosing high-density human-cancer cells promotes vascularized <i>in vivo</i> tumor modeling for immune cell therapyDOI 10.1101/2024.12.17.628981
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