Article

Kinase-independent activity of DYRK1A promotes viral entry of highly pathogenic human coronaviruses

2022-09-14

Abstract excerpt

<h4>ABSTRACT</h4> Identifying host genes essential for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has the potential to reveal novel drug targets and further our understanding of coronavirus disease 2019 (COVID-19). We previously performed a genome-wide CRISPR/Cas9 screen to identify pro-viral host factors for highly pathogenic human coronaviruses. Very few host factors were required by diverse c...

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Literature Corpus work: d678e610-f163-592b-b37b-4289a58d10be
DOI: 10.1101/2022.09.13.507833

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