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DYRK1A promotes viral entry of highly pathogenic human coronaviruses in a kinase-independent manner

13 Jun 2023

Abstract excerpt

Identifying host genes essential for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has the potential to reveal novel drug targets and further our understanding of Coronavirus Disease 2019 (COVID-19). We previously performed a genome-wide CRISPR/Cas9 screen to identify proviral host factors for highly pathogenic human coronaviruses. Few host factors were required by diverse coronaviruses across...

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PMID: 37310920
DOI: 10.1371/journal.pbio.3002097

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