Article

Easy and efficient ensemble gene set testing with EGSEA

2017-11-14

Abstract excerpt

Gene set enrichment analysis is a popular approach for prioritising the biological processes perturbed in genomic datasets. The Bioconductor project hosts over 80 software packages capable of gene set analysis. Most of these packages search for enriched signatures amongst differentially regulated genes to reveal higher level biological themes that may be missed when focusing only on evidence from individual genes....

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 212f47b5-0ae6-53d9-89ae-25e17a6576e1
DOI: 10.12688/f1000research.12544.1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Easy and efficient ensemble gene set testing with EGSEADOI 10.12688/f1000research.12544.1Read

Combining multiple tools outperforms individual methods in gene set enrichment analysesSemantic proximity Read

Towards a gold standard for benchmarking gene set enrichment analysisSemantic proximity Read

RichPathR: a gene set enrichment analysis and visualization toolSemantic proximity Read

The Molecular Signatures Database Revisited: Extending Support for Mouse DataSemantic proximity Read

Evaluation of Gene Set Enrichment Analysis (GSEA) tools highlights the value of single sample approaches over pairwise for robust biological discoverySemantic proximity Read

Gene set enrichment; a problem of pathways.Semantic proximity Read

Comparative study of gene set enrichment methods.Semantic proximity Read

FITdb, an Integrated Functional Immunogenomics and Transcriptomics DatabaseSemantic proximity Read

GSVA: gene set variation analysis for microarray and RNA-seq data.Semantic proximity Read

Differential Expression Enrichment Tool (DEET): An interactive atlas of human differential gene expressionSemantic proximity Read

Benchmarking enrichment analysis methods with the disease pathway networkSemantic proximity Read

SEAHORSE: A Serendipity Engine Assaying Heterogeneous Omics-Related Sampling ExperimentsSemantic proximity Read