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Article

GSVA: gene set variation analysis for microarray and RNA-seq data.

BMC bioinformatics - 16 Jan 2013

Hänzelmann Sonja, Castelo Robert, Guinney Justin

Abstract excerpt

BACKGROUND: Gene set enrichment (GSE) analysis is a popular framework for condensing information from gene expression profiles into a pathway or signature summary. The strengths of this approach over single gene analysis include noise and dimension reduction, as well as greater biological interpretability. As molecular profiling experiments move beyond simple case-control studies, robust and flexible GSE...

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Identifiers

PMID: 23323831
DOI: 10.1186/1471-2105-14-7
PMCID: PMC3618321

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