Article

Proximity proteomics of primary cilia in human hypothalamic neurons

2025-05-12

Abstract excerpt

Primary cilia are hair-like sensory organelles that project from the cell bodies of most cell types, including appetite-regulatory hypothalamic neurons where they likely help sense metabolic factors to regulate food intake. We hypothesized that characterising the proteins present in the primary cilia of hypothalamic neurons would shed mechanistic insights into their sensory role and identify new therapeutic target...

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Literature Corpus work: d65f26b1-a877-5517-9b90-acb382840197
DOI: 10.1101/2025.05.11.653368

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Semantic proximity does not establish scientific evidence.

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