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Global reprogramming of virulence and antibiotic resistance in <i>Pseudomonas aeruginosa</i> by a single nucleotide polymorphism in the elongation factor-encoding gene, <i>fusA1</i>

2019-11-15

Abstract excerpt

Pseudomonas aeruginosa is a common opportunistic pathogen. The organism displays elevated intrinsic antibiotic resistance and can cause life-threatening infections. The gene encoding an elongation factor, FusA1, is frequently mutated in clinical isolates of P. aeruginosa from patients with cystic fibrosis (CF). Recent work has shown that fusA1 mutants often display elevated aminoglycoside resistance due to incre...

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Literature Corpus work
d63cf29d-aa96-5865-9cc3-90ff185c8771
DOI
10.1101/842781
Open publication

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Global reprogramming of virulence and antibiotic resistance in <i>Pseudomonas aeruginosa</i> by a single nucleotide polymorphism in the elongation factor-encoding gene, <i>fusA1</i>DOI 10.1101/842781
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