Article

miRNA-mediated inhibition of an actomyosin network in hippocampal pyramidal neurons restricts sociability in adult male mice

2023-11-12

Abstract excerpt

Social deficits are frequently observed in patients suffering from neurodevelopmental disorders, but the molecular mechanisms regulating sociability are still poorly understood. We recently reported that the loss of the microRNA cluster miR-379-410 leads to hypersocial behavior and anxiety in mice. Here, we show that ablating miR-379-410 in excitatory neurons of the postnatal mouse hippocampus recapitulates hypers...

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Literature Corpus work: d62a5859-ef05-50d8-9b47-cb5ab4e08c48
DOI: 10.1101/2023.11.08.566242

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miRNA-mediated inhibition of an actomyosin network in hippocampal pyramidal neurons restricts sociability in adult male miceDOI 10.1101/2023.11.08.566242Read

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