Article

Metadichol® induced expression of circadian clock transcription factors in human fibroblasts

2024-02-21

Abstract excerpt

The circadian clock genes play a significant role in various aspects of health and disease, including sleep, metabolism, inflammation, and cancer. CRY1, BMAL1, PER1, PPARGC1A, and CLOCK are key circadian clock genes that govern the daily rhythms of diverse physiological processes in mammals. These genes create a feedback loop called a transcriptional-translational feedback loop (TTFL). In this loop, the heterodime...

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Literature Corpus work: 0ee218cd-03a0-50c6-84c5-3794470f9644
DOI: 10.1101/2024.02.21.581403

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