Article

Nociceptor neuroimmune interactomes reveal cell type- and injury-specific inflammatory pain pathways

2023-02-03

Abstract excerpt

Inflammatory pain associated with tissue injury and infections, results from the heightened sensitivity of the peripheral terminals of nociceptor sensory neurons in response to exposure to inflammatory mediators. Targeting immune-derived inflammatory ligands, like prostaglandin E2, has been effective in alleviating inflammatory pain. However, the diversity of immune cells and the vast array of ligands they produce...

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Literature Corpus work: d58df4bd-bd7d-59cf-807a-6410c7c65541
DOI: 10.1101/2023.02.01.526526

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