Article

Design characteristics of Sequential Multiple Assignment Randomized Trials (SMARTs) for human health: a scoping review of studies between 2009-2024

2025-06-08

Abstract excerpt

<h4>STRUCTURED ABSTRACT</h4> <h4>Objective</h4> To characterize the reporting practices of sequential multiple assignment randomized trials (SMARTs) in human health research. <h4>Design</h4> Scoping review of protocol and primary analysis papers describing SMARTs published between January 2009 and February 2024. <h4>Background</h4> SMARTs are innovative trial designs that allow for multiple stages of randomiza...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d57d56a4-bdf3-5892-a1f8-de682898a313
DOI: 10.1101/2025.06.06.25329149

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Design characteristics of Sequential Multiple Assignment Randomized Trials (SMARTs) for human health: a scoping review of studies between 2009-2024DOI 10.1101/2025.06.06.25329149Read

Randomized trials of ‘personalized’, ‘individualized’ and ‘precision’ interventions are very diverse and have low transparency and high biasSemantic proximity Read

A Methodological Review of Randomised n-of-1 Trials.Semantic proximity Read

Simulation and minimization: Technical advances for factorial experiments designed to optimize clinical interventionsSemantic proximity Read

Inverse probability weighted estimation of dynamic treatment regimen means in sequential multiple assignment randomised trials with missing data: a simulation studySemantic proximity Read

A Sequential Multiple Assignment Randomized Trial Design with Response-Adaptive Tailoring FunctionSemantic proximity Read

Methodological review to develop a list of bias items for adaptive clinical trials: Protocol and rationaleSemantic proximity Read

Demographic Representation of a Decentralized Long COVID Trial: A Comparison with the 2023 National Health Interview SurveySemantic proximity Read

Part II: Adaptive designs in pediatric clinical trials: specific examples, comparison with adult trials and a discussion for the child health communitySemantic proximity Read

State of play in individual participant data meta-analyses of randomised trials: Systematic review and consensus-based recommendationsSemantic proximity Read

Statistical Considerations for the Design and Analysis of Pragmatic Trials in Aging ResearchSemantic proximity Read

PROTOCOL: LLM-Generated CONSORT Report for Increased Reporting: A Parallel-Arm Randomized Controlled TrialSemantic proximity Read

The Call for Progress in Evidence-Based MedicineSemantic proximity Read