Article

State of play in individual participant data meta-analyses of randomised trials: Systematic review and consensus-based recommendations

2026-02-04

Abstract excerpt

<h4>Background</h4> Individual participant data (IPD) meta-analyses obtain, harmonise and synthesise the raw individual-level data from multiple studies, and are increasingly important in an era of data sharing and personalised medicine to inform clinical practice and policy. <h4>Objectives</h4> (1) Describe the landscape of IPD meta-analysis of randomised trials over time; (2) establish current practice in desi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: db0bd70c-82b4-5d24-b2f9-d09fec982cd3
DOI: 10.64898/2026.02.03.26345481

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

State of play in individual participant data meta-analyses of randomised trials: Systematic review and consensus-based recommendationsDOI 10.64898/2026.02.03.26345481Read

Assessing the Secondary Use and Scientific Impact of Shared Clinical Trial Data: A Cross-Sectional Study of Clinical Trials Shared on the YODA Project PlatformSemantic proximity Read

A general framework for using two-stage meta-analysis with individual participant data to predict individualized treatment effectsSemantic proximity Read

Methodological Challenges using Routine Clinical Care Data for Real-World Evidence: a Rapid Review utilizing a systematic literature search and focus group discussionSemantic proximity Read

Meta-Mar: An AI-Assisted Web Platform for Accessible and Rigorous Meta-AnalysisSemantic proximity Read

The PRISMA 2020 statement: an updated guideline for reporting systematic reviewsSemantic proximity Read

Development of a checklist to detect errors in meta-analyses in systematic reviews of interventions: study protocolSemantic proximity Read

(Semi)automated approaches to data extraction for systematic reviews and meta-analyses in social sciences: A living review protocolSemantic proximity Read

Randomized trials of ‘personalized’, ‘individualized’ and ‘precision’ interventions are very diverse and have low transparency and high biasSemantic proximity Read

Prevalence and Methodological Characteristics of Subgroup Analyses in Stepped Wedge Cluster Randomised Trials: Protocol for a Systematic ReviewSemantic proximity Read

Onlinemeta: A Web Server for Meta-Analysis Based on Shiny FrameworkSemantic proximity Read

Design characteristics of Sequential Multiple Assignment Randomized Trials (SMARTs) for human health: a scoping review of studies between 2009-2024Semantic proximity Read