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Application of single-cell sequencing in human cancer

25 Oct 2017

Abstract excerpt

Precision medicine is emerging as a cornerstone of future cancer care with the objective of providing targeted therapies based on the molecular phenotype of each individual patient. Traditional bulk-level molecular phenotyping of tumours leads to significant information loss, as the molecular profile represents an average phenotype over large numbers of cells, while cancer is a disease with inherent intra-tumour...

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PMID: 29106464
DOI: 10.1093/bfgp/elx036

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