Article

Altered Expression of the MEG3–FTO–ATF4 Axis and Lipid Metabolism Genes in PBMCs from Children with Obesity and Its Associations and Added Sugar Intake

2025-07-11

Abstract excerpt

<h4>Background: </h4> Obesity and its complications have increased in both adults and children, with pediatric populations developing metabolic disorders earlier ages. Long non-coding RNAs, particularly MEG3, are involved in obesity through regulation of lipid metabolism genes including ATF4, FTO, SREBP1, FASN, and ACACA. However, data on MEG3 expression in pediatric obesity are limited. This study evaluated MEG3,...

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Literature Corpus work: d53ce574-1fa8-5e06-aebe-9e3f5cfcaca6
DOI: 10.20944/preprints202507.0922.v1

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Altered Expression of the MEG3–FTO–ATF4 Axis and Lipid Metabolism Genes in PBMCs from Children with Obesity and Its Associations and Added Sugar IntakeDOI 10.20944/preprints202507.0922.v1Read

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