Article
Variants in GHRL, RETN, and PLIN1 are associated with obesity, diabetes, and metabolic syndrome, and influence food consumption in adults with obesity.
Nutrition research (New York, N.Y.) - 1 Feb 2025
Dos Santos Marina Aparecida, Bortolin Raul Hernandes, Cerda Alvaro, de Oliveira Raquel, Stefani Tamires Invencioni Moraes, Fajardo Cristina Moreno, Dorea Egídio Lima, Bernik Márcia Martins Silveira, Damasceno Nágila Raquel Teixeira, Hirata Mario Hiroyuki, Hirata Rosario Dominguez Crespo
Abstract excerpt
Genetic and environmental factors have important role in the pathogenesis of obesity and metabolic diseases. We hypothesized that genes involved in energy intake, cellular lipid metabolism and pro-inflammatory adipokines influence obesity-related metabolic disturbances and food intake. We explored the association of GHRL (rs26311G>C and rs4684677A>T), PLIN1 (rs2289487G>A and rs894160G>A), RETN (rs3745367C>T and...
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