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Delayed booster dosing improves human antigen-specific Ig and B cell responses to the RH5.1/AS01<sub>B</sub> malaria vaccine

2022-04-27

Abstract excerpt

<h4>Background</h4> Antibodies are crucial for vaccine-mediated protection against many pathogens. Modifications to vaccine delivery that increase antibody magnitude, longevity, and/or quality are therefore of great interest for maximising efficacy. We have previously shown that a delayed fractional (DFx) dosing schedule (0-1-6mo) – using AS01 B -adjuvanted RH5.1 malaria antigen – substantially improves serum IgG...

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Literature Corpus work
d5315484-b193-515e-b9d6-200d657b4d91
DOI
10.1101/2022.04.25.22274161
Open publication

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Delayed booster dosing improves human antigen-specific Ig and B cell responses to the RH5.1/AS01<sub>B</sub> malaria vaccineDOI 10.1101/2022.04.25.22274161
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