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Article

Regulation of autophagy by transforming growth factor-β (TGF-β) signaling

24 Jun 2010

Abstract excerpt

Transforming growth factor-β (TGF-β) has broad impacts on an array of diverse cellular functions including cell growth, differentiation, adhesion, migration, and apoptosis. Perturbations of the TGF-β signaling pathways are involved in progression of various tumors. Autophagy is a pivotal response of normal and cancer cells to environmental stresses and is induced by various stimuli. Otherwise, autophagy has an...

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PMID: 20458184
DOI: 10.4161/auto.6.5.12046

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