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LncRNA MALAT1 aggravates high glucose-induced renal tubular epithelial injury via activating LIN28A and the Nox4/AMPK/mTOR signaling axis

2022-06-06

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<title>Abstract</title> <p>Background Diabetic nephropathy (DN) is a serious complication among patients with diabetes. Elucidating its pathogenesis is crucial for identifying novel biomarkers and therapeutic targets for DN. Methods DN tissues were harvested for examining MALAT1, LIN28A and Nox4. Human kidney-2 (HK-2) cells were treated with high glucose (HG) for establishing a cell model of DN. Cell viability...

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Literature Corpus work
222e9f9d-d55f-5005-9017-d43a6001368d
DOI
10.21203/rs.3.rs-1655817/v1
Open publication

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