Article

Impaired formation and updating of internal predictive models in a rat model of Fragile X Syndrome

2026-08-25

Abstract excerpt

Predictive coding frameworks propose that perception emerges from a continuous comparison of incoming sensory signals with internally generated predictions, with mismatches between the two computed as prediction errors. Disruptions to the balance between these top-down predictions and bottom-up sensory signals are theorized to contribute to sensory abnormalities in neuropsychiatric conditions like autism spectrum...

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Literature Corpus work: 5e93f5f5-323f-50fc-8615-b215764bf5e1
DOI: 10.64898/2026.08.20.746021

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