Article

“Single-nucleus RNA-seq2 reveals a functional crosstalk between liver zonation and ploidy”

2020-07-12

Abstract excerpt

Single-cell RNA-seq reveals the role of pathogenic cell populations in development and progression of chronic diseases. In order to expand our knowledge on cellular heterogeneity we have developed a single-nucleus RNA-seq2 method that allows deep characterization of nuclei isolated from frozen archived tissues. We have used this approach to characterize the transcriptional profile of individual hepatocytes with di...

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Literature Corpus work: d48ee92a-2367-56f6-90e5-18478a8052e1
DOI: 10.1101/2020.07.11.193458

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