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Article

The origin and evolution of ARGFX homeobox loci in mammalian radiation.

BMC evolutionary biology - 17 Jun 2010

Li Guang, Holland Peter W H

Abstract excerpt

BACKGROUND: Many homeobox genes show remarkable conservation between divergent animal phyla. In contrast, the ARGFX (Arginine-fifty homeobox) homeobox locus was identified in the human genome but is not present in mouse or invertebrates. Here we ask when and how this locus originated and examine its pattern of molecular evolution. RESULTS: Phylogenetic and phylogenomic analyses suggest that ARGFX originated by...

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Identifiers

PMID: 20565723
DOI: 10.1186/1471-2148-10-182
PMCID: PMC2894831

Genes

ARGFX

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