Article
Diagnosis, risk stratification, and response evaluation in classical myeloproliferative neoplasms.
Blood - 9 Feb 2017
Rumi Elisa, Cazzola Mario
Abstract excerpt
Philadelphia-negative classical myeloproliferative neoplasms (MPNs) include polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF). The 2016 revision of the WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues includes new criteria for the diagnosis of these disorders. Somatic mutations in the 3 driver genes, that is, JAK2, CALR, and MPL, represent major diagnostic...
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