Early hemostatic responses to trauma identified with hierarchical clustering analysis.

doi:10.1111/jth.12919

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Article

Early hemostatic responses to trauma identified with hierarchical clustering analysis.

Journal of thrombosis and haemostasis : JTH - 1 Jun 2015

White N J, Contaifer D, Martin E J, Newton J C, Mohammed B M, Bostic J L, Brophy G M, Spiess B D, Pusateri A E, Ward K R, Brophy D F

Abstract excerpt

BACKGROUND: Trauma-induced coagulopathy is a complex multifactorial hemostatic response that is poorly understood. OBJECTIVES: To identify distinct hemostatic responses to trauma and identify key components of the hemostatic system that vary between responses. PATIENTS/METHODS: A cross-sectional observational study of adult trauma patients at an urban level I trauma center emergency department was performed....

Topics

Adult
Bayes Theorem
Biomarkers
Blood Coagulation
Blood Coagulation Tests
Cluster Analysis
Cross-Sectional Studies
Discriminant Analysis
Female
Fibrinogen
Fibrinolysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hemostasis

Humans

Inflammation Mediators

Injury Severity Score

Male

Middle Aged

Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 25816845
DOI: 10.1111/jth.12919
PMCID: PMC4452397

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