Article
Insights into human genetic variation and population history from 929 diverse genomes.
Science (New York, N.Y.) - 20 Mar 2020
Bergström Anders, McCarthy Shane A, Hui Ruoyun, Almarri Mohamed A, Ayub Qasim, Danecek Petr, Chen Yuan, Felkel Sabine, Hallast Pille, Kamm Jack, Blanché Hélène, Deleuze Jean-François, Cann Howard, Mallick Swapan, Reich David, Sandhu Manjinder S, Skoglund Pontus, Scally Aylwyn, Xue Yali, Durbin Richard, Tyler-Smith Chris
Abstract excerpt
Genome sequences from diverse human groups are needed to understand the structure of genetic variation in our species and the history of, and relationships between, different populations. We present 929 high-coverage genome sequences from 54 diverse human populations, 26 of which are physically phased using linked-read sequencing. Analyses of these genomes reveal an excess of previously undocumented common...
Topics
- Africa
- Americas
- Animals
- Asia
- DNA Copy Number Variations
- Genetic Variation
- Genetics, Population
- Genome, Human
- Haplotypes
- Hominidae