Article
STRA6 is critical for cellular vitamin A uptake and homeostasis.
Human molecular genetics - 15 Oct 2014
Amengual Jaume, Zhang Ning, Kemerer Mary, Maeda Tadao, Palczewski Krzysztof, Von Lintig Johannes
Abstract excerpt
Vitamin A must be adequately distributed within the body to maintain the functions of retinoids in the periphery and chromophore production in the eyes. Blood transport of the lipophilic vitamin is mediated by the retinol-binding protein, RBP4. Biochemical evidence suggests that cellular uptake of vitamin A from RBP4 is facilitated by a membrane receptor. This receptor, identified as the Stimulated by retinoic...
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