Article

Protection of insect neurons by erythropoietin/CRLF3-mediated regulation of pro-apoptotic acetylcholinesterase

2022-03-15

Abstract excerpt

<title>Abstract</title> <p>Cytokine receptor-like factor 3 (CRLF3) is a highly conserved but largely uncharacterized orphan cytokine receptor that shares structural similarity with vertebrate classical erythropoietin receptor. CRLF3-mediated neuroprotection in insects can be stimulated with human erythropoietin and involves partly similar anti-apoptotic mechanisms as erythropoietin-mediated neuroprotection in mam...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d413b3ca-0c33-531d-868f-83b9ae803fac
DOI: 10.21203/rs.3.rs-1435358/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Protection of insect neurons by erythropoietin/CRLF3-mediated regulation of pro-apoptotic acetylcholinesteraseDOI 10.21203/rs.3.rs-1435358/v1Read

The Insect Ortholog of the Human Orphan Cytokine Receptor CRLF3 Is a Neuroprotective Erythropoietin ReceptorSemantic proximity Read

The Orphan Cytokine Receptor CRLF3 Emerged With the Origin of the Nervous System and Is a Neuroprotective Erythropoietin Receptor in LocustsSemantic proximity Read

Human cytokine receptor CRLF3 is a receptor for the neuroprotective erythropoietin splice variant EV-3Semantic proximity Read

Acetylcholinesterase promotes apoptosis in insect neuronsSemantic proximity Read

The cytokine receptor CRLF3 is a human neuroprotective EV-3 (Epo) receptorSemantic proximity Read

Dramatic increase in readthrough acetylcholinesterase in a cellular model of oxidative stress.Semantic proximity Read

SC35 promotes sustainable stress-induced alternative splicing of neuronal acetylcholinesterase mRNASemantic proximity Read

Agonists of melatonin receptors strongly promote the functional recovery from the neuroparalysis induced by neurotoxic snakesSemantic proximity Read

Endogenous mechanisms of neuroprotection.Semantic proximity Read

Predicted overlapping microRNA regulators of acetylcholine packaging and degradation in neuroinflammation-related disordersSemantic proximity Read

Homeoprotein neuroprotection of embryonic neuronal cellsSemantic proximity Read

Repeated Intravenous Administration of Human Neural Stem Cells Encoding Choline Acetyltransferase Gene Exhibits Anti-ageing Activities Displaying Enhanced Cognitive and Physical FunctionsSemantic proximity Read