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Article

Dramatic increase in readthrough acetylcholinesterase in a cellular model of oxidative stress.

Journal of neurochemistry - 1 Mar 2011

Härtl Ricarda, Gleinich Anne, Zimmermann Martina

Abstract excerpt

Moderate, transient oxidative stress is achieved in SH-SY5Y cells using tertiary butylhydroperoxide as oxidant. Over a recovery period of 24 h, the enzymatic activity and protein levels of the acetylcholinesterase (AChE) splice variants tailed AChE (AChE-T) and readthrough AChE (AChE-R) are monitored. Their time-dependent correlation to pro- and anti-apoptotic factors, namely caspase 3 and Bcl-2, respectively, as...

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PMID: 21198638
DOI: 10.1111/j.1471-4159.2010.07164.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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