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Article

Acetylcholinesterase promotes apoptosis in insect neurons

5 Aug 2020

Abstract excerpt

Apoptosis plays a major role in development, tissue renewal and the progression of degenerative diseases. Studies on various types of mammalian cells reported a pro-apoptotic function of acetylcholinesterase (AChE), particularly in the formation of the apoptosome and the degradation of nuclear DNA. While three AChE splice variants are present in mammals, invertebrates typically express two ache genes that code...

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PMID: 32761307
DOI: 10.1007/s10495-020-01630-4

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