Article

Development and Evaluation of Deuterated [ 18 F]JHU94620 Isotopologues for the Non-invasive Assessment of the Cannabinoid Type 2 Receptor in Brain

2024-10-24

Abstract excerpt

Background and Purpose: The cannabinoid type 2 receptors (CB2R) represent a target of increasing importance in neuroimaging due to its upregulation under various neuropathological conditions. Previous evaluation of [ 18 F]JHU94620 for the non-invasive assessment of the CB2R availability by positron emission tomography (PET) revealed favourable binding properties and brain uptake, however rapid metabolism, and gen...

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Literature Corpus work: d3fa38e0-afb0-55de-8bb1-04bc7824adc8
DOI: 10.22541/au.172979832.20556552/v1

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