Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The significance of epithelial–mesenchymal transition (EMT) in the initiation, plasticity, and treatment of glioblastoma

6 Jun 2025

Abstract excerpt

Epithelial‒mesenchymal transition (EMT) is a dynamic cellular process in which epithelial cells lose their characteristics and acquire mesenchymal traits, leading to enhanced migratory, invasive, and stem-like properties. EMT is a fundamental mechanism in cancer progression, including in glioblastoma (GBM), an aggressive brain tumor known for its poor prognosis and resistance to treatment. In GBM, EMT has been...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to FOXO transcription factor regulation
Share to Glioma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 41141394
DOI: 10.1016/j.gendis.2025.101711

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The significance of epithelial–mesenchymal transition (EMT) in the initiation, plasticity, and treatment of glioblastomaPMID 41141394Read ↗

Molecular drivers of epithelial-mesenchymal transition (EMT) in glioblastoma and impact on therapy resistanceSemantic proximity Read ↗

Epithelial-mesenchymal transition in glioblastoma progressionSemantic proximity Read ↗

Epithelial–mesenchymal transition in cancer development and its clinical significanceSemantic proximity Read ↗

The molecular mechanisms and therapeutic strategies of EMT in tumor progression and metastasisSemantic proximity Read ↗

Factors Determining Epithelial-Mesenchymal Transition in Cancer ProgressionSemantic proximity Read ↗

The Epithelial-Mesenchymal Transition and Cancer Stem Cells: Functional and Mechanistic LinksSemantic proximity Read ↗

Comprehensive understanding of glioblastoma molecular phenotypes: classification, characteristics, and transition.Semantic proximity Read ↗

Genomics and Prognosis Analysis of Epithelial-Mesenchymal Transition in GliomaSemantic proximity Read ↗

Epithelial to Mesenchymal Transition in a Clinical PerspectiveSemantic proximity Read ↗

Roles of genetic and microenvironmental factors in cancer epithelial-to-mesenchymal transition and therapeutic implication.Semantic proximity Read ↗

Proneural-Mesenchymal Transition: Phenotypic Plasticity to Acquire Multitherapy Resistance in GlioblastomaSemantic proximity Read ↗

The role of epithelial-mesenchymal transition in regulating radioresistanceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.