Article
The aggregation of α-synuclein and its inhibtion
2019-01-01
Abstract excerpt
The aggregation of the human brain protein alpha-synuclein is associated with Parkinson's disease and a host of other neurodegenerative diseases termed the synucleinopathies. In this thesis is described aspects of the pathophysiology of alpha-synuclein and that of six point mutants associated with familial Parkinson's disease, as well as strategies aimed at impeding the aggregation process. A novel ten-residue pep...
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Identifiers and source
- Literature Corpus work
- d3defdfc-615f-537e-9173-6767b258dc55
- DOI
- 10.17638/03059871