Article

Mining for disease-associated microbial metabolites in an age-dependent model of multiple sclerosis

2024-06-01

Abstract excerpt

Age is a risk factor for the neurological decline and physical disability that characterize progressive multiple sclerosis (MS). The intestinal microbiota and the bioactive compounds it produces can influence aging, immunity, and the central nervous system (CNS). Here, we use an experimental autoimmune encephalomyelitis (EAE) model that mimics features of progressive MS in aged, but not young, mice to address the...

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Literature Corpus work: d3ddbee1-5681-5fd2-8b22-3078274196f7
DOI: 10.1101/2024.05.27.595846

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